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The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles, and editorial opinion on a wide variety of topics of . Explore the current issue of The New England Journal of Medicine (Vol. 394 No. 13). Oct 8, 2025 · AI in Medicine explores the history and vast potential of artificial intelligence and machine learning across all areas of health care. Feb 18, 2026 · This Sounding Board announces a new FDA policy that the default requirement for FDA approvals will be one robust pivotal trial plus confirmatory evidence, rather than two trials.